(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental dates: 15-18 October 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP. The substance is adequately characterised. Therefore full validation applies.

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

July 27, 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

Commission Regulation (EC) No 440/2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: ISO 304 – Surface Active Agents – Determination of surface tension by drawing up liquid films

Version / remarks:

1985-12-15

GLP compliance:

yes (incl. QA statement)

Remarks:

signed on 15 Nov. 2018

Type of method:

OECD harmonised ring method

Specific details on test material used for the study:

Storage conditions: Ambient temperature away from light. Kept in the original container.

Key result

Surface tension:

50.6 mN/m

Temp.:

20.4 °C

Conc.:

45.3 mg/L

Remarks on result:

other: expected 90% of saturation

Measurements on reference substances complied with the validation criteria.

First Determination

Mean of 5 stable values = 50.8 mN/m

Temperature: 20.6 - 20.5°C

Second Determination

Mean of 5 stable values = 50.5 mN/m

Temperature: 20.5 - 20.3°C

As the mean surface tensions obtained with trials 1 and 2 do not differ by more than 0.5 mN/m, no additional trial is needed.

The mean value of 50.6 mN/m is retained for final result.

Conclusions:

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions.

Executive summary:

The surface tension of the test substance was measured under GLP according to OECD 115/EU A5 guidelines, using the ring method.

The apparatus was calibrated with a mass.

Two determinations were performed, on two indepenent solutions prepared by diluting saturated solutions to 90%. Actual concentrations were not checked. Their surface tension was then determined from five consecutive consistent measurements. The final result was the mean of two consistent determinations.

The surface tension of the test solution (ca 45.3 mg/L) at 20.4°C was 50.6 mN/m.

Description of key information

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions. However, since the structure is not characteristic of a true surfactant, and it is not the intended use of the substance (i.e. not a desired property), this conclusion should be taken with caution.

Key value for chemical safety assessment

Surface tension:

50.6

in mN/m at 20°C and concentration in mg/L:

45.3

Additional information

Based on the chemical structure, showing no alert, and considering the substance is not intended to be used as a surfactant, no further data should be required.

However, a fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available.

Therefore, it is considered as a key study, and the result is retained as key data. It should be noted that actual concentration was not checked, but calculated as 90% expected of the water solubility.