Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 953-704-3 | CAS number: 2411191-47-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental Dates: 14 to 22 October 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. The substance is adequately characterised. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- March 23, 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Regulation (EC) No 440/2008, with last update to the A.4 method by Commission Regulation (EC) No 761/2009
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- signed on 15 Nov. 2018
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- Actual storage conditions: Ambient temperature away from light. Kept in the original container.
- Temp.:
- 20 °C
- Vapour pressure:
- 5 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 8.7 Pa
- Conclusions:
- Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
- Executive summary:
The vapour pressure of the test substance was measured, under GLP, according to OECD 104 / EU A4 guideline, using the Knudsen effusion method.
Two trials were performed. For each trial, five pairs temperature/mass loss were used to calculate corresponding vapour pressure of the substance at temperatures between ca 25 and 50°C. Then the logarithm of the vapour pressure log10 (VP(Pa)) is plotted against 1/T(K), and the regression curve is
used to calculate the vapour pressure of the substance at 20°C and 25°C.
The vapour pressure of the test substance is 5.0 Pa at 20°C and 8.7 Pa at 25°C.
Reference
First trial
| Temperature (°C) | Vapour pressure (Pa) |
| 22.8 | 6.8759 |
| 26.0 | 9.3675 |
| 32.7 | 20.0684 |
| 39.8 | 41.7752 |
| 47.6 | 83.4240 |
A plot of log10 (VP) versus reciprocal temperature (1/T) (with VP in Pa and T in K) gives the following relationship:
Log10 (VP (Pa)) = -4206.8/ T (K) + 15.048
R² = 0.9992
The above equation yields a vapour pressure of 4.99 Pa at 293.15 K and 8.69 Pa at 298.15 K.
Second trial
| Temperature (°C) | Vapour pressure (Pa) |
| 22.7 | 6.8382 |
| 26.0 | 9.3307 |
| 32.4 | 19.7705 |
| 39.5 | 41.7740 |
| 47.1 | 83.9106 |
A plot of log10 (VP) versus reciprocal temperature (1/T) (with VP in Pa and T in K) gives the following relationship:
Log10 (VP (Pa)) = -4294.0 / T (K) + 15.342
R² = 0.9991
The above equation yields a vapour pressure of 4.94 Pa at 293.15 K and 8.70 Pa at 298.15 K.
The test item did not change in appearance under the conditions used in the determination.
Mean of trials 1 and 2: 4.97 Pa at 293.15 K (20°C) and 8.70 Pa at 298.15 K (25°C).
Description of key information
Low volatility.
Key value for chemical safety assessment
- Vapour pressure:
- 8.7 Pa
- at the temperature of:
- 25 °C
Additional information
A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study. The interpolated result at 25°C is retained as key value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
