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EC number: 231-212-3 | CAS number: 7447-41-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- According to REACH Regulation (EC) No 1907/2006, Annex XI, section 1.3, the used QSAR model needs to be scientifically validated and the substance has to fit in the applicability domain of the used model. EPI Suite v4.10 is a collection of physical/chemical property and environmental fate estimation models developed by the EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC). It is a screening level tool which gives adequate results for the purpose of classification and labelling and/or risk assessment. In addition, the used QSAR estimation tool is recommended by ECHA and can be found in Table R.7.1-21 in the REACH Guidance on information requirements and chemical safety assessment (2008), chapter R.7.1.7.3.. Thus, the calculated value is reliable with restrictions.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR Estimation with MPBPWIN v1.43
- Deviations:
- no
- Principles of method if other than guideline:
- Chapter 2 of Lyman (1985) describes the modified Grain method used by MPBPWIN. This method is a modification and significant improvement of the modified Watson method. It is applicable to solids, liquids and gases. The modified Grain method equations can be found in the publication. The KF structural factors are available in chapter 14 of Lyman et al (1990); the variation of this parameter is related to chemical class and is small (roughly 0.99 to 1.2), so large errors in its selection are unlikely (Lyman, 1985). The modified Grain method may be the best all-around VP estimation method currently available.
- GLP compliance:
- not specified
- Type of method:
- other: Modified Grain Method
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- A vapour pressure of 4.2E-30 Pa was calculated for lithium chloride using EPI Suite v4.10.
- Executive summary:
Lithium chloride is a solid at room temperature and normal atmospheric pressure. The boiling point is very high as it decomposes 1360°C. It can be assumed that the vapour pressure is nearly 0 Pa for lithium chloride at normal atmospheric conditions. The calculation of the vapour pressure of lithium chloride with EPI Suite v4.10 can be seen as estimation as no inorganic compounds were included in the training data set of the program. But taken into account the high boiling point this EPI Suite estimation can be regarded as adequate enough to be used for risk assessment.
The vapour pressure of lithium chloride was estimated using MPBPWIN v1.43 embedded in EPI Suite v4.10 of EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC). The program is a screening level tool and estimates the vapour pressure of chemicals using three separate methods. The modified Grain method was chosen as it may be the best vapour pressure estimation method currently available. A vapour pressure of 4.2E-30 Pa was derived for lithium chloride.
Reference
Description of key information
According to column 2 of REACH Regulation 1907/2006 Annex VII, section 7.5, it is stated, that if the melting point is above 300 °C a study is not required and if it is between 200 °C and 300 °C, a limit value based on a recognized calculation method is sufficient. Lithium chloride has a melting point that is in the range of 608 - 614 °C. A vapour pressure of 4.2E-30 Pa at 25 °C was calculated with the modified Grain method (EPISuite, v4.10, supporting study record).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.