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EC number: 609-080-7 | CAS number: 35160-38-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In one key study with Daphnia magna (OECD 202) no effects were observed at nominal concentrations of the test item phoshinic acid, diethyl-, sodium salt up to 1100 mg/L (NOEC 1100 mg/L).
This is supported by three acute immobilization tests with Daphnia magna according to OECD Guideline 202.
Two studies performed with the read across substance phosphinic acid, diethyl, aluminium salt result in 48 h-EC50 values > 100 mg/L based on the nominal test item concentration. The NOEC after 48 h was 100 mg/L.
The third test was performed with the read across substance diethyl, phosphinic acid. Based on the nominal concentrations of the test item the 48-h EC50 for Daphnia magna was estimated to be 70.7 mg/L. The NOEC after 48 h was 50.0 mg/L. The LOEC after 48 h was 100 mg/L.
The effects observed at the concentration level of 100 mg/L were caused by the low pH-values (pH below the recommended range of pH 6 – 9). This was confirmed by the pH-neutralized concentration level of 100 mg/L which caused no effects on Daphnia magna. Based on the pH-neutralized concentration the 48-h EC50 and the NOEC for Daphnia magna were > 100 mg/L.
Key value for chemical safety assessment
Additional information
In one key study with Daphnia magna (OECD 202) no effects were observed at nominal concentrations of the test item phoshinic acid, diethyl-, sodium salt up to 1100 mg/L (NOEC 1100 mg/L).
This is supported by three acute immobilization tests with Daphnia magna according to OECD Guideline 202.
Two studies performed with the read across substance phosphinic acid, diethyl, aluminium salt result in 48 h-EC50 values > 100 mg/L based on the nominal test item concentration. The NOEC after 48 h was 100 mg/L.
The third test was performed with the read across substance diethyl, phosphinic acid. Based on the nominal concentrations of the test item the 48-h EC50 for Daphnia magna was estimated to be 70.7 mg/L. The NOEC after 48 h was 50.0 mg/L. The LOEC after 48 h was 100 mg/L.
The effects observed at the concentration level of 100 mg/L were caused by the low pH-values (pH below the recommended range of pH 6 – 9). This was confirmed by the pH-neutralized concentration level of 100 mg/L which caused no effects on Daphnia magna. Based on the pH-neutralized concentration the 48-h EC50 and the NOEC for Daphnia magna were > 100 mg/L.
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