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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Study period:
1976
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Poor characterization of inhaled material. Unknown particle size.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Principles of method if other than guideline:
Animals are exposed to dust generated by blowing air through the sample.
GLP compliance:
no
Test type:
other: inhalation harzard test
Limit test:
yes

Test material

Constituent 1
Reference substance name:
[[2,2',2''-[29H,31H-phthalocyaninetriyltris(methylene)]tris[1H-isoindole-1,3(2H)-dionato]](2-)-N29,N30,N31,N32]copper
EC Number:
261-638-5
EC Name:
[[2,2',2''-[29H,31H-phthalocyaninetriyltris(methylene)]tris[1H-isoindole-1,3(2H)-dionato]](2-)-N29,N30,N31,N32]copper
Cas Number:
59160-79-1
IUPAC Name:
261-638-5

Test animals

Species:
rat
Sex:
male/female
Details on test animals or test system and environmental conditions:
Mean body weight: 191 g

Administration / exposure

Route of administration:
inhalation: dust
Type of inhalation exposure:
whole body
Vehicle:
air
Analytical verification of test atmosphere concentrations:
yes
Remarks:
gravimetrically
Duration of exposure:
8 h
Concentrations:
5.95 mg/l
No. of animals per sex per dose:
12
Control animals:
other: air control
Details on study design:
Particle size distribution not determined.

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LC0
Effect level:
>= 5 mg/L air
Based on:
test mat.
Exp. duration:
8 h
Remarks on result:
other: Particle size distribution unknown
Mortality:
None
Clinical signs:
other: Slight mucosal irritation
Gross pathology:
Nothing abnormal detected

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU