Registration Dossier
Registration Dossier
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EC number: 200-842-0 | CAS number: 75-12-7
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- QSARS for the eye irritation potential of neutral organic chemicals.
- Author:
- Barratt, MD
- Year:
- 1 997
- Bibliographic source:
- Toxic in Vitro 11, 1-8.
Materials and methods
- Type of study / information:
- Type: other: QSAR (eye irritation)
Test material
- Reference substance name:
- Formamide
- EC Number:
- 200-842-0
- EC Name:
- Formamide
- Cas Number:
- 75-12-7
- Molecular formula:
- CH3NO
- IUPAC Name:
- formamide
- Details on test material:
- formamide
Constituent 1
Results and discussion
Any other information on results incl. tables
RS-Freetext:
A Quantitative Structure-Activity Relationship (QSAR) was
derived previously relating European Community (EC) eye
irritation classification data of a set of neutral organic
chemicals, to log (octanol/water partition coefficient), to
minor principal inertial axes (Ry and Rx) and to dipole
moment. Eye irritation classification predicted by this QSAR
model was compared with in vivo data.
Formamide was classified as non-irritant by both QSAR and in
vivo data.
Applicant's summary and conclusion
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