Registration Dossier
Registration Dossier
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EC number: 448-010-8 | CAS number: - VALDECOXIB
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove to fresh air, monitor blood pressure, respiration,
temperature and general condition. Get medical attention
promptly.
Emergency measure - Eyes: Immediately flush eyes with large amounts of water for 15
minutes. Get prompt medical attention.
Emergency measure - Skin: Remove contaminated clothing. Wash skin with soap and
water. Get medical attention if irritation develops.
Emergency measure - Ingestion: Provide general support and monitor blood pressure,
respiration, temperature and general condition. Get medical
attention promptly.
Fire-fighting measures
Recommended extinguishing agent: Use dry chemical, carbon dioxide, water spray, regular foam
or extinguishing agent suitable for surrounding fire.
Product arising from burning: Oxides of nitrogen and sulfur.
Product determined by test: N
Protective equipment: Fire fighters should wear pressure demand self-contained
breathing apparatus and full protective gear.
Accidental release measures
Emergency measures in case of spillage: Vacuum material with high efficiency particulate air (HEPA)
filter vacuum cleaner or wet sweep. Collect waste for
proper disposal. Keep unnecessary people away. Do not
flush spilled material into sewer.
Handling and storage
Handling: Use with adequate ventilation. Avoid breathing dust. Avoid
contact with eyes, skin or clothing.
During processing in Ireland, workers should
wear the following personal protective equipment:
Air Suit:
Positive pressure full/half air suits (Plysu suits)-
compressed airline breathing appartus:material-duraskin.
Complies with BS EN943-1
Respirator:
'Gemini' RFF60 Fullface Respirator. Silicone rubber mask.
Complies with BS EN136. Visor complies with EN166. Standard
thread filter connection to BS EN148-1. Filter PRO2000 CF32-
EN141.2000/EN12941/EN 12942 (ABEKP3)
Gloves:
'N-Dex' 7005 P/Free Nitrile Gloves. Complies with BS EN374
Eye Protection:
Denver 'Roma' Safety Spectacles, polycarbonate lens. BS
EN166:1996 (EU Directive 89/686/EEC (CE Mark Category 2)
Storage: No special storage provisions are necessary.
Packaging of the substance and or preparation: The test substance will be imported in 39 gal fibre drums.
Transport information
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport code: Not classified for transport.
Transport: Containers should be transported upright and secured against
falling over. Containers should be suitably labelled and
securely sealed.
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: Not known.
Chemical reaction with water: Not known.
Dust explosion: The test substance is an organic powder, therefore, care
should be taken to avoid possible sources of ignition. The
test substance is not highly flammable, but will burn in a
fire.
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: It is not possible to recover or recycle the used test
substance.
Industry - Possibility of neutralisation: No applicable
Industry - Possibility of destruction: controlled discharge: Not applicable.
Industry - Possibility of destruction - incineration: Incineration is the preferred method.
Industry - Possibility of destruction - water purification: Not applicable
Industry - Possibility of destruction - other: None known
Public at large - Possibility of recovery/recycling: Not applicable, as the public at large is not exposed to the
test substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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