Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-472-8 | CAS number: 107-20-0
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC of a 96 h test of fertilized zebra fish eggs in the 8-cell stage with chloroacetaldehyde (1 - 100 mg/L) resulted in a NOEC (development) of 6 mg/L. No deaths or morphological changes were observed in the controls (fish embryos without test substances). Chloroacetaldehyde produced malformations in the fish embryos with lesions mainly of the heart or skeleton. Oedematous enlargement of the pericardial space with retardation of heart development and reduced blood flow was observed under the treatment with chloroacetaldehyde was observed. A deformation of the skeleton and the muscle apparatus appeared in the embryos after administration of chloroacetaldehyde. The underlying cause of death could not be determined explicitly in the embryos, even though an obvious association between malformations and death existed.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
