Registration Dossier
Registration Dossier
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EC number: 937-559-3 | CAS number: 1360085-10-4
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- sodium 7-[(ethoxycarbonyl)amino]-4-hydroxynaphthalene-2-sulfonate
- EC Number:
- 937-559-3
- Cas Number:
- 1360085-10-4
- Molecular formula:
- C13H12NNaO6S
- IUPAC Name:
- sodium 7-[(ethoxycarbonyl)amino]-4-hydroxynaphthalene-2-sulfonate
- Details on test material:
- 85.2 % active substance
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
- Details on test animals or tissues and environmental conditions:
- 1 male
2 females
Results and discussion
Any other information on results incl. tables
Animal Mean values 24 - 72 hours
Cornea Iris Conjunctivae
Opacity Redness Chemosis
male 0.00 0.00 0.33 0.33
female 0.00 0.00 0.33 0.67
female 0.00 0.00 1.00 1.00
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information
- Conclusions:
- Based on the results described above and according to classification criteria of EEC Commission Directive 93/21/EEC (April 27, 1993), the test substance is classified as "not irritating" to the rabbit eye.
- Executive summary:
not irritating
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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