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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: extracted from ECHA database
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
EC Number:
406-030-4
EC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
Cas Number:
105812-81-5
Molecular formula:
C13H18FNO
IUPAC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine

Study design

Oxygen conditions:
not specified
Inoculum or test system:
not specified
Duration of test (contact time):
28 d
Reference substance
Reference substance:
benzoic acid, sodium salt

Results and discussion

% Degradationopen allclose all
Parameter:
not specified
Value:
43
Sampling time:
28 d
Parameter:
not specified
Value:
13
Sampling time:
15 d
Parameter:
not specified
Value:
12
Sampling time:
5 d

BOD5 / COD results

Results with reference substance:
96% after 5 d
99% after 15 d
100 % after 28 d

Applicant's summary and conclusion

Interpretation of results:
not inherently biodegradable
Conclusions:
As 43% biodegradation was observed at 28 days, the substance is not considered to be readily biodegradable and it cannot be considered as unduly toxic to activated sludge micro-organism.