Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Does not meet criteria of current guidelines.

Data source

Reference
Reference Type:
review article or handbook
Title:
Unpublished data Eastman Kodak.
Author:
Fassett, D.W.
Year:
1963
Bibliographic source:
Summarized in Patty's Industrial Hygiene and Toxicology 2nd Ed. Interscience Publishers, New York, New York.

Materials and methods

Principles of method if other than guideline:
Method: other: "drop on" technique
GLP compliance:
no
Type of study:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-mercaptopropionic acid
EC Number:
203-537-0
EC Name:
3-mercaptopropionic acid
Cas Number:
107-96-0
Molecular formula:
C3H6O2S
IUPAC Name:
3-sulfanylpropanoic acid
Details on test material:
no data

In vivo test system

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
not specified

Results and discussion

Any other information on results incl. tables

Since the results at the final evaluation were similar to those seen in the early part of the study,
3-mercaptopropionic acid was considered to have been negative in the sensitization study.

Applicant's summary and conclusion

Interpretation of results:
ambiguous
Remarks:
Migrated information
Conclusions:
The reported data do not allow a valid conclusion.