Registration Dossier
Registration Dossier
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EC number: 445-790-1 | CAS number: 404362-22-7
Endpoint summary
Administrative data
Description of key information
Additional information
C&L for short-term toxicity:
The acute aquatic toxicity of the test item was tested in short-term tests on the toxicity to algae, daphnids and fish. The results were given as loading rates WAF (i.e. Water Accomodated Fraction), as the test item is poorly soluble, consists of four major components with different water solubility levels and Kow values. It is therefore not possible to assign the toxic effects to a certain component of the test item. The results were as follows:
Organism |
LL50 or EL50 |
Fish |
4.0 mg/L |
Daphnia |
3.4 mg/L |
Algae (growth) |
0.15 mg/L |
With an EL50 < 1.0 mg/L observed in the algal toxicity study, this leads to following classification:
CLP: Aquatic Acute Toxicity Category 1; H400: Very toxic to aquatic life
DSD: N; R50: Very toxic to aquatic organisms
C&L for long-term toxicity:
In the algae toxicity test, which is considered as a multi generation study, a No Effect Loading rate (NOELR) for growth rate of 0.04 mg/L was obtained. In a 21-day reproductive toxicity study in daphnids the NOEC was 0.14 mg/L.
Referring to the algae study, the substance has to be classified for chronic aquatic hazard according to the second amendment of Regulation (EC) No 1272/2008 (CLP), which requests for non-rapidly degradable substances (see section biodegradation and hydrolysis) with NOEC < 0.1 mg/L following classification:
CLP: Aquatic Chronic Toxicity Category 1; H410: Very toxic to aquatic life with long lasting effects
DSD: N; R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
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