Registration Dossier
Registration Dossier
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EC number: 619-127-3 | CAS number: 95418-58-9
Endpoint summary
Administrative data
Description of key information
The toxicity to the aquatic environment of butoxystyrene was investigated in accordance with Annex VII of REACH by performing GLP-compliant short-term toxicity studies to freshwater aquatic invertebrates and algae.
Short-term toxicity to aquatic invertebrates (Daphnia magna): the acute toxicity of butoxystyrene was assessed in a GLP-compliant study according to OECD202. No acute immobilisation was induced by butoxystyrene at 1.1 mg/l after 48h of exposure (NOEC). The 48h-EC50 was 3.8 mg/l based on average exposure concentrations.
Toxicity to aquatic algae: a GLP-compliant fresh water algal growth inhibition study was performed with butoxystyrene according to OECD201. The 72h ErC50 was >4.8 mg/l and the NOEC for growth rate reduction was 1.2 mg/l.
Considering that the lowest EC50 for butoxystyrene is above 1 mg/L, the substance does not meet the criteria for EU CLP classification as Aquatic Acute 1.
A GLP-compliant study was conducted to determine the ready biodegradability of butoxystyrene according to OECD301B (CO2 evolution test). The relative degradation values calculated from the measurements performed during the test period revealed no significant degradation of butoxystyrene. Butoxystyrene was considered to be not readily biodegradable.
Considering that the lowest EC50 for butoxystyrene is between 1 and 10 mg/L and the substance is not readily biodegradable, butoxystyrene meets the criteria for EU CLP classification as Aquatic Chronic 2.
Additional information
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