Diamminediisocyanatozinc

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

until 1986-11-13

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

Study was attempted, but substance decomposes.

GLP compliance:

no

Other quality assurance:

other: self-stated

Type of method:

column elution method

Water solubility:

ca. 0.1 g/L

Incubation duration:

2 h

Temp.:

20 °C

Remarks on result:

other: A standard test was performed to provide an apparent solubility of the test item in water and was estimated to be approximately 10exp(-2) g/l at room temperature (approximately 20°C).

pH values of the prepared mixtures are given in Table 1 and results of microanalysis on the isolated solids in Table 2.

 

Table 1 pH of test item – water mixtures

Mixture	Initial pH	pH after 2 h
A	8.59	8
B	8.57	8
C	8.57	8

 

The pH of distilled water prior to use was 6.1.

 

Table 2 Microanalysis of isolated solids

Sample	Empirical Formula	C2H6N4O2Zn
		Analysis
		% C	% H	% N
	Theory	13.07	3.29	30.64
Test item	Found	12.46	2.62	29.91
A	Found	4.21	1.45	4.44
B	Found	4.16	1.43	4.24
C	Found	4.31	1.48	4.60

 

Thermal instability of the test item at 50 °C over a 24 h time period has been reported elsewhere. However, the level of decomposition was much less than indicated here for decomposition of the test item in water. Therefore, it was concluded that the drying of isolated solids at 40 °C for approximately 2 h prior to microanalysis did not significantly contribute to the overall finding of gross decomposition. The pH measurements of water mixtures of the test item were consistent with rapid decomposition accompanied by release of ammonia.

The test item was therefore found to be unstable in water at 25 °C over a time period of 2 h.

Conclusions:

0.009 g of the test material did not dissolve in 100 ml of water but formed a flocculate. However, on making up to 1000 ml and leaving for 24 hours the flocculate appeared to disperse. The apparent solubility was therefore described as ~ 10exp(-2)

Executive summary:

The test item was found to be unstable in water at 25 °C over a time period of two hours. Decomposition precludes measurement of the water solubility of essentially pure material according to OECD test guidelines. However, a standard test was performed to provide an apparent solubility and this was estimated to be approximately 10^-2g/l at room temperature (approximately 20 °C). The physical process studied appeared to be one of dispersion rather than dissolution.

Description of key information

Water solubility, OECD 105: The test item was found to be unstable in water at 25 °C over a time period of two hours, solubility was estimated to be approximately 10^-2g/l

Key value for chemical safety assessment

Water solubility:

0.1 g/L

at the temperature of:

20 °C

Additional information

The test item was found to be unstable in water at 25 °C over a time period of two hours. Decomposition precludes measurement of the water solubility of essentially pure material according to OECD test guidelines. However, a standard test was performed to provide an apparent solubility and this was estimated to be approximately 10^-2g/l at room temperature (approximately 20 °C). The physical process studied appeared to be one of dispersion rather than dissolution.