2-(4-Bromphenyl)-5-butyl-1,3-dioxane, trans-

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-12-04 to 2018-02-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

349.3 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 320 - 380 °C. The onset temperature (see Table 2) was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. No further endothermic or exothermic effects were observed up to the final temperature (400 °C and 500 °C, respectively). The mass loss after the DSC measurements amounted 100 %.

 

Table 2: Boiling point (DSC measurement)

Test item / mg	Starting temperature / °C	Final test temperature / °C	Temperature range (endothermal) / °C	Onset (boiling)/ °C	Crucible	Observations after the measurement
14.09	25	500	320 -380	349.85	Aluminium with a hole	Mass loss: 100%
16.74	25	400	325 -375	349.94	Aluminium with a hole	Mass loss: 100%

 

For the correction delta t of the boiling point to standard atmospheric pressure (1013.3 hPa) the equation, table and graphs of H.B. Hass and R.F. Newton in "CRC Handbook of Chemistry and Physics, 74th ed. 1993-1994, pages 15-16 and 15-17 were use. The test item had a mean boiling point at atmospheric pressure (1013.3 hPa) of 349.3 °C.

Conclusions:

The boiling point of the test item was determined to be 349.3 °C at 1013.25 hPa.

Executive summary:

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OCSPP test guideline 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 14 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. Two DSC measurements with a heating rate of 10 K/min in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 320 -380 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. The correction of the boiling temperature to standard pressure was performed according to H.N. Hass and R.F. Newton. A boiling point of the test item of 349.3 °C corrected to normal atmospheric pressure was determined. No further thermal effects were observed up to the maximum test temperature of 500 °C.

Description of key information

The boiling point of the test item was determined to be 349.3 °C at 1013.25 hPa (reference 4.3 -1).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

349.3 °C

Additional information

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OCSPP test guideline 830.7220 to determine the boiling point of the test item using differential scanning calorimetry (reference 4.3 -1). The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 14 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. Two DSC measurements with a heating rate of 10 K/min in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 320 -380 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. The correction of the boiling temperature to standard pressure was performed according to H.N. Hass and R.F. Newton. A boiling point of the test item of 349.3 °C corrected to normal atmospheric pressure was determined. No further thermal effects were observed up to the maximum test temperature of 500 °C.