Registration Dossier
Registration Dossier
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EC number: 687-893-6 | CAS number: 1150560-54-5
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 10 -May 15 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- not specified
- Type of method:
- flask method
Test material
- Reference substance name:
- 1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- EC Number:
- 687-893-6
- Cas Number:
- 1150560-54-5
- Molecular formula:
- C13H9F4IN2O2
- IUPAC Name:
- 1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- Purity: 100%
Batch No.: FTIM31803002
Expiration date: Mar 10, 2019 (retest date)
Physical status: Off- white powder
Results and discussion
Water solubility
- Key result
- Water solubility:
- 0.966 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- > 24 h
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- The mean result of water solubility of Methyl iodouracil was 0.966mg/L at 20°C, the RSD% was 2.47% (n=3).
Applicant's summary and conclusion
- Conclusions:
- Based on the test results the water solubility of Methyl iodouracil was 0.966mg/L at 20°C, the RSD% was 2.47% (n=3).
- Executive summary:
The water solubility of Methyl iodouracil was determined compatiible with the Principles of OECD Guidlies for testing of chemicals no. 105 'Water Solubility'. Based on the test results the water solubility of Methyl iodouracil was 0.966mg/L at 20°C, the RSD% was 2.47% (n=3).
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