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EC number: 217-100-7 | CAS number: 1739-83-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1,2,4,5-tetramethyl-1H-imidazole
- EC Number:
- 217-100-7
- EC Name:
- 1,2,4,5-tetramethyl-1H-imidazole
- Cas Number:
- 1739-83-9
- Molecular formula:
- C7H12N2
- IUPAC Name:
- tetramethyl-1H-imidazole
Constituent 1
- Specific details on test material used for the study:
- Name 1,2,4,5-Tetramethylimidazole
Batch no. EV7YH
Appearance white crystalline powder
Composition 1,2,4,5-Tetramethylimidazol： ≥98%
CAS No. 1739-83-9
EC-No. 217-100-7
Molecular formula C7H12N2
Molecular weight 124.187 g/mol
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- ca. 28 d
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 9
- Sampling time:
- 28 d
Any other information on results incl. tables
The test item1,2,4,5-Tetramethylimidazolewas tested using a concentration of nominally 20 mg organic carbon/L1,2,4,5-Tetramethylimidazolein test medium following OECD 301B and EU-Method C.4-C.
Aniline was chosen as positive control.
Activated sludge was used as inoculum (concentration in the test 25.0 mg dry matter/L). The test was left running for 28 days.
All validity criteria were met. Degradation of the positive control surpassed the pass level of 60 % after 7 days.
The following data were determined for the test item1,2,4,5-Tetramethylimidazole:
10-day-window: not
detected
degradation at the end of
10-day-window none
degradation at the end of the
test 9
%
pass level following
guideline: 60 % at the end of 10-day-window for pure substances
respective 60 % at the end of the test for mixtures
Therefore, when applying the 10-day-window, the test item1,2,4,5-Tetramethylimidazoleisnotreadily biodegradablefollowing OECD 301B and EU C.4-C respectively. As degradation missed the pass level of 60% in the course of the test,1,2,4,5-Tetramethylimidazoleis considered asnotultimately biodegradable,after 28 days, as well.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
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