Ethylene di(S-thioacetate)

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

not specified

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)

Deviations:

not specified

GLP compliance:

not specified

Remarks:

the test was conducted in an academic setting without GLP certification

Specific details on test material used for the study:

technical grade, no further information

Oxygen conditions:

aerobic

Inoculum or test system:

sewage, predominantly domestic, non-adapted

Details on inoculum:

- Source of inoculum/activated sludge: STP of Lüneburg, Germany (144,000 inhabitant
equivalents)
- Initial cell/biomass concentration: two drops of effluent per L

Duration of test (contact time):

28 d

Key result

Parameter:

% degradation (O2 consumption)

Value:

78.3

St. dev.:

1.6

Sampling time:

28 d

Remarks on result:

other: OECD 301D (CBT)

Key result

Parameter:

% degradation (O2 consumption)

Value:

65.9

St. dev.:

5.4

Sampling time:

28 d

Remarks on result:

other: OECD 301F (MRT)

Biodegradation test results obtained in the present study. For each experiment the % O₂consumption in the two parallel bottles is given, and for valid results the average ±SD, otherwise the criterion rendering a result invalid.

Compound name (abbreviation) [CAS-RN]	Experiment number	OECD 301D (CBT)		OECD 301F (MRT)
		O2Consumption/ ThOD [%]	Average in a valid experiment ±SD	O2Consumption/ ThOD [%]	Average in a valid experiment ±SD
TGA and derivatives
Thioglycolic acid (TGA) [68-11-1]	1	31.8, 45.3	38.5 ±9.5	114.4, 92.1	not valid, criterion 1
	2	49.2, 51.3	50.2 ±1.5	78.8, 94.4	86.6 ±11.1
Diammonium dithiodiglycolate (DADTDG, TGA disulfide ammonium salt) [68223-93-8]	1 calculated without nitrification	123.8, 106.4	115.1 ±12.3	130.0, 132.0	131.0 ±1.4
	1 re-calculated with nitrification	76.6, 65.9	71.3 ±7.6	80.5, 81.7	81.1 ±0.9
	2 calc. with nitrification	14.9, 29.2	22.0 ±10.1	79.4, 90.8	85.1 ±8.0
	3 calc. with nitrification	90.9, 86.0	88.5 ±3.5
Dithiodiglycolic acid (DTDGA, TGA disulfide) [505-73-7]	1	65.9, 62.2	64.1 ±2.6	87.9, 111.2	not valid, criterion 1
	2			60.3, 55.7	58.0 ±3.3
2-Ethylhexyl thioglycolate (2-EHTG) [7659-86-1]	1*	58.3, 61.2	59.7 ±2.0	28.2, 54.7	not valid, criterion 1
	2*			18.4, 13.9	16.2 ±3.2
Isotridecyl thioglycolate (iC13TG)^a [57417-85-3]	1**	1.4, 10.0	not valid, criterion 4	40.9, 22.5	31.7 ±13.0
	2**	14.6, 9.5	12.0 ±3.6
Glycol di(mercaptoacetate) (GDMA) [123-81-9]	1	62.2^b	not valid, criterion 1	62.1, 69.8	65.9 ±5.4
	2	82.5, 72.4	not valid, criterion 4
	3	70.0^b	not valid, criterion 1
	4	79.4, 77.1	78.3 ±1.6
Glyceryl monothioglycolate^a(GMT) [30618-84-9]	1	56.0, 50.7	53.4 ±3.7	79.8, 80.8	80.3 ±0.7

^amulticonstituent substance (MCS), for details see Experimental

^bresult from one test bottle only, the other one became leaky during the experiment

^*due to poor solubility, this substance was directly weighed in MRT

^**due to very poor solubility, this substance was directly weighed both in CBT and MRT

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

Based on 78% biodegradation in a closed bottle test, GDMA is readily biodegradable.

Description of key information

Based on predicted 78 % biodegradation, GDMA is expected to be readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Type of water:

freshwater