Farnesol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

16 October 2014 - 17 October 2014

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Remarks:

Boiling point was determined during a melting point study. Although the boiling point was not explicitly determined, the experimental method and results are robust and adequate to derive a reliable boiling point value.

Justification for type of information:

Boiling point was determined as part of a melting point study using differential scanning calorimetry. Although adherence to the boiling point method was not reported, the experimental method and results are reliable and adequate to derive a boiling point for the test item.

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 103 (Boiling Point/Boiling Range)

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Principles of method if other than guideline:

Boiling point was determined as part of a melting point study using differential scanning calorimetry. Although adherence to the boiling point method was not reported, the experimental method and results are reliable and adequate to derive a boiling point for the test item.

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 296.6 - <= 299.5 °C

Atm. press.:

>= 994 - <= 996.8 hPa

Decomposition:

no

Table 1. Results of the DSC measurements

Sample number	Sample weight (mg)	Onset of effect (°C)	Range of effect (°C)	Weight loss (mg)	Atmospheric pressure (hPa)
1	14.99	296.58	220 - 350 (endothermic)	14.99	994.0
2	13.20	299.54	170 - 340 (endothermic)	13.20	996.8

During the heating phase the test item showed an endothermic signal in the temperature range of approx. 170 – 350 °C that can be associated with the boiling of the test item. No further thermal effects were observed up to the maximum test temperature of 500 °C.

Conclusions:

The boiling point of the test item is 296.6 to 299.5°C at 994.0 to 996.8 hPa.

Executive summary:

The boiling point of the test item is 296.6 to 299.5°C at 994.0 to 996.8 hPa, as determined by differential scanning calorimetry. This study is considered reliable with restriction (Klimisch 2) as it was determined as part of a melting point study. Adherence to a boiling point method was not reported, however the experimental method and results are reliable and adequate to derive a boiling point for the test item.

Description of key information

The boiling point of the test item is 296.6 to 299.5°C at 994.0 to 996.8 hPa. As multi-constituent substances do not have a consistent melting/boiling point, a boiling range is reported.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

297 °C

Additional information

The boiling point of the test item was determined by differential scanning calorimetry (2015). This study is considered reliable with restriction (Klimisch 2) as it was determined as part of a melting point study. Adherence to a boiling point method was not reported, however the experimental method and results are reliable and adequate to derive a boiling point for the test item. Supporting data are also available from two peer-reviewed handbooks (2009, 2006) for individual constituents (isomers) of the substance.