Registration Dossier
Registration Dossier
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EC number: 286-282-8 | CAS number: 85203-90-3
Endpoint summary
Administrative data
Description of key information
Hydrolysis
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical 2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl) azo] phenyl] azo]-, ar-styrenated can be expected to be 6 yrs and 211 days at pH 7 and 8, respectively with a second order hydrolysis rate constant of 0.038 L/mol-sec and was reported to be hydrolytically stable at pH 4, 7 and 9, respectively & at a temperature of 50⁰C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical 2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl) azo] phenyl] azo]-, ar-styrenated is not hydrolysable.
Additional information
Hydrolysis
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical 2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl) azo] phenyl] azo]-, ar-styrenated (CAS no. 85203 -90 -3).The studies are as mentioned below:
The half-life of the test chemical was determined at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C. Although, half-life value of test chemical is not known, but chemical was reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of 50⁰C. Based on this, it is concluded that test chemical is not hydrolysable.
In an another study, the half-life and base catalyzed second order hydrolysis rate constant was determined using a structure estimation method of the test chemical. The second order hydrolysis rate constant of test chemical was determined to be 0.038 L/mol-sec with a corresponding half-lives of 6 yrs and 211 days at pH 7 and 8, respectively. Based on the half-life values, it is concluded that test chemical is not hydrolysable.
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical 2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl) azo] phenyl] azo]-, ar-styrenated can be expected to be 6 yrs and 211 days at pH 7 and 8, respectively with a second order hydrolysis rate constant of 0.038 L/mol-sec and was reported to be hydrolytically stable at pH 4, 7 and 9, respectively & at a temperature of 50⁰C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical 2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl) azo] phenyl] azo]-, ar-styrenated is not hydrolysable.
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