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Toxicity to aquatic algae and cyanobacteria

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toxicity to aquatic algae and cyanobacteria
Type of information:
Adequacy of study:
supporting study
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
Test organisms (species):
other: Green algae
Test type:
other: (Q)SAR
Water media type:
96 h
Dose descriptor:
Effect conc.:
98.07 mg/L
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
26.669 mg/L
Validity criteria fulfilled:
Aliphatic Amines: Maximum LogKow: 7.0 (Green Algae EC50) - 7.0 (Chronic Value)
Estimated EC50 (96h) : 98 mg/L
Estimated Chronic Value : 26 mg/L
Intermediate substance is estimated to be harmful to aquatic algae (Acute Toxicity).

Description of key information

Short-term toxicity:

ECOSAR 1.11: Green Algae: EC50 (96h): 98.070mg/L

Danish (Q)SAR Database: Pseudokirchneriella s. 72h EC50:

Battery: 1015 mg/L

Leadscope: 1999 mg/L

SciQSAR: 30.29 mg/L


Long-term toxicity:

Indicated results for chronic toxicity are "Chronic values" as obtained from ECOSAR 1.11

ECOSAR 1.11: Green Algae: ChV: 26.669 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
98 mg/L
EC10 or NOEC for freshwater algae:
26 mg/L

Additional information

NOEC could be estimated to around 18 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is estimated to be harmful to aquatic algae (Acute toxicity).