Registration Dossier
Registration Dossier
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EC number: 207-988-4 | CAS number: 504-29-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 004
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Data from peer reviewed handbook. No data provided on methods.
- GLP compliance:
- not specified
- Test type:
- other: not specified.
Test material
- Reference substance name:
- 2-pyridylamine
- EC Number:
- 207-988-4
- EC Name:
- 2-pyridylamine
- Cas Number:
- 504-29-0
- Molecular formula:
- C5H6N2
- IUPAC Name:
- pyridin-2-amine
Constituent 1
- Specific details on test material used for the study:
- - pyridin-2-amine / 504-29-0 / 207-988-4
- State: powder
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 200 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Remarks:
- EU criteria
- Conclusions:
- According to handbook data, the oral DL50 for rat is 200 mg/kg bw.
- Executive summary:
According to 'Sax's Dangerous Properties of Industrial Materials', 11th edition, 'Kirk-Othmer Encyclopedia of Chemical Technology', and Patty’s Toxicology, 6th Edition, (peer reviewed handbook data), the oral DL50 for rat is 200 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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