Registration Dossier
Registration Dossier
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EC number: 600-265-8 | CAS number: 1020409-50-0
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 113 Screening test for thermal stability and stability in air
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- >= 206 - <= 212 °C
- Atm. press.:
- ca. 1 013 hPa
Reference
DSC measurements in aluminium crucibles with a hole showed an endothermal effect in the temperature range of 150 -225°C with onset temperatures between 206.12°C and 211.83°C. A second endothermal effect was observed in the temperature range of 320 -345°C with an unsteady onset. From the results of DSC measurements it was concluded that the test item had a melting range of 206 -212°C. The second endothermal effect in the temperature range 320 -345°C was not interpreted as boiling since approx. 50% of the test item mass remain as black residue and the DSC-measurement in a closed glass crucible showed an exothermal signal in the temperature range of 280°C and 350°C. It was concluded that the test item had no boiling point. The test item decomposed prior to boiling.
Description of key information
The melting point /melting range are determined by differential scanning calorimetry (DSC) according to EU Method A.1 and OECD Guideline 102. The test item 4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro-, phosphate (1:2) had a melting range 206-212°C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 206 °C
Additional information
The test item 4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro-, phosphate (1:2) had a melting range 206-212°C.
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