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EC number: 210-283-4 | CAS number: 611-92-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17.06.2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 2.82
- Temp.:
- 25 °C
- pH:
- 6.31
- Conclusions:
- The partition coefficient of the test substance Methylcentralit is: log P = 2.82 0.70 (25 °C, pH = 6.31)
- Executive summary:
The partition coefficient of the test substance, Methylcentralit, was determined.
Based on the results of the preliminary estimation of the partition coefficient by a calculation method, the HPLC method was used for the main experiment.
The procedure was performed according to Method A.8. – Partition Coefficient,Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.
Partition coefficient (log P) of the test substance,Methylcentralit,is:
log P = 2.82 0.70 (25 °C, pH = 6.31)
Reference
Description of key information
Only one study is available.
Method A.8. – Partition Coefficient, Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.
GLP study.
Klimish score 1.
Partition coefficient (log P) of the test substance, Methylcentralit is: log P = 2.82 (25 °C, pH = 6.31)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.82
- at the temperature of:
- 25 °C
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