Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 915-277-1 | CAS number: 32052-51-0
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Adequacy of study:
- supporting study
- Study period:
- 1972
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
- Study type:
- human medical data
Test material
- Reference substance name:
- Trimethylhexa-1,6-diyl diisocyanate
- EC Number:
- 249-151-6
- EC Name:
- Trimethylhexa-1,6-diyl diisocyanate
- Cas Number:
- 28679-16-5
- Molecular formula:
- C11H18N2O2
- IUPAC Name:
- 1,6-Diisocyanatotrimethylhexane
Constituent 1
Method
- Details on study design:
- - Test persons: 3 male volunteers
- Exposure: Whole body inhalation, short time (not quantified) 0.01 ppm; 0.05 ppm; 0.1 ppm; 1.0 ppm
Results and discussion
- Results:
- - 0.01 ppm: Not perceptible
- 0.05 ppm: Slight irritation of eyes and nose, odor not perceptible
- 0.10 ppm: Distinct irritation of eyes and nose, musty odor
- 1.0 ppm: Severe irritation of mucosa (eyes, nose, throat), acceptable only for a short duration
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
