Registration Dossier
Registration Dossier
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EC number: 237-706-5 | CAS number: 13933-32-9
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP status not known, non-guideline experimental study, limitations in design and/or reporting but otherwise adequate for assessment.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- A saturated solution of the test item in water was prepared. A volume of this solution was then removed and diluted with an aliquot of water before analysis by ICP-OES. The PGM content of the solution is back-calculated from the ICP-OES result.
- GLP compliance:
- not specified
- Type of method:
- flask method
- Water solubility:
- 240 other: g tetraammineplatinum dichloride/ kg solution
- Temp.:
- 20 °C
- Remarks on result:
- other: pH; not reported; temperature: room temperature, nominally 20°C
- Details on results:
- As a determination of the solution density has not been performed the results are in g per kg solution not g/L.
- Conclusions:
- The solubility of tetraammineplatinum dichloride has been reported as 240 g tetraammineplatinum dichloride/Kg solution.
- Executive summary:
This is a non-GLP, non-guideline experimental study. Although there are some limitations in the design or reporting of the study, the method used is considered to be acceptable and therefore the study is considered to be adequate for assessment of this endpoint. The solubility of tetraammineplatinum dichloride has been reported as 240 g tetraammineplatinum dichloride/Kg solution.
Reference
Results table
| Product | CAS | PGM-content (%) | sat. Solution (g) | Water added (g) | PGM cont (%) | Solubility (g product/kg solution) |
| Tetraammineplatinum dichloride | 13933-32-9 | 55.8 | 6.06 | 5.68 | 6.9 | 240 |
Description of key information
The solubility of tetraamminplatinum dichloride is 240 g product/kg solution.
Key value for chemical safety assessment
- Water solubility:
- 240 g/L
- at the temperature of:
- 20 °C
Additional information
The results are from a non-guideline experimental study (Winde 2011). There are some limitations in the design or reporting of the study but the method followed is considered to be acceptable and therefore this study is considered to be adequate for assessment of this endpoint. The solubility of tetraammineplatinum dichloride has been reported as 240 g product/kg solution at room temperature.
This is supported by data from a reliable handbook that states that tetraammine platinum dichloride is soluble (Lewis 2007).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
