Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 928-842-2 | CAS number: 1184648-08-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96h), fish [(R)-2-(4-hydroxyphenoxy)-propanoic acid] > 100 mg/L (Rufli 1995)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
(R)-2-(4-hydroxyphenoxy)-propanoic acid (CAS 94050-90-5) was tested for acute toxicity to fish by using an acute fish toxicity test under GLP according to OECD Guideline 203 and EU Method C.1. The results of the test showed no mortality, neither in the 100 mg/l test item nor in the control group. Also no sublethal effects were noticed. Therefore, the LC50 (96h) was determined to be > 100 mg/l and the NOEC to be 100 mg/l.
Potassium (R)-2-(4-hydroxyphenoxy)propionate, when dissolved in water becomes equal to the test item (R)-2-(4-hydroxyphenoxy)propanoic acid and toxicity to fish of the potassium salt is therefore equal to the toxicity to fish measured for the acid. It can therefore be concluded by read-across without reasonable doubt that the LC50 (96h) of potassium (R)-2-(4-hydroxyphenoxy)propionate is >100 mg/L and the NOEC is 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
