Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Annales Pharmaceutiques Francaises. Vol. 41
Year:
1983
Bibliographic source:
ChemIDplus - Annales Pharmaceutiques Francaises. Vol. 41, Pg. 391

Materials and methods

Principles of method if other than guideline:
No guideline reported
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-hydroxybenzonitrile
EC Number:
212-175-2
EC Name:
4-hydroxybenzonitrile
Cas Number:
767-00-0
Molecular formula:
C7H5NO
IUPAC Name:
4-hydroxybenzonitrile
Test material form:
solid: crystalline

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
450 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Conclusions:
The substance is classified Harmful if swallowed.