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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: not applicable
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(4-aminophenyl)-2,5-dihydro-1,2,4-oxadiazol-5-one
EC Number:
917-912-8
Cas Number:
864680-71-7
Molecular formula:
C8 H7 N3 O2
IUPAC Name:
3-(4-aminophenyl)-2,5-dihydro-1,2,4-oxadiazol-5-one

Results and discussion

Any other information on results incl. tables

Calculations with EPISuite 4.11 (BIOWIN v4.10) give the following results:

Biowin1 (Linear Model Prediction) : Does Not Biodegrade

Fast Biowin2 (Non-Linear Model Prediction): Does Not Biodegrade Fast

Biowin3 (Ultimate Biodegradation Timeframe): Weeks-Months

Biowin4 (Primary Biodegradation Timeframe): Days-Weeks

Biowin5 (MITI Linear Model Prediction) : Not Readily Degradable

Biowin6 (MITI Non-Linear Model Prediction): Not Readily Degradable

Biowin7 (Anaerobic Model Prediction): Does Not Biodegrade fast

Fast Ready Biodegradability Prediction: NO

Applicant's summary and conclusion

Interpretation of results:
other: not readily biodegradable
Conclusions:
Based on QSAR-Calculations it can be predicted, that the test substance is not readily biodegradable.