Registration Dossier
Registration Dossier
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EC number: 220-027-3 | CAS number: 2610-10-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Few details available on test procedures.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no guideline available
- GLP compliance:
- not specified
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- Hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate]
- EC Number:
- 220-027-3
- EC Name:
- Hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate]
- Cas Number:
- 2610-10-8
- Molecular formula:
- C45H32N10O21S6.6Na
- IUPAC Name:
- hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulpho
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
- Details on test animals or test system and environmental conditions:
- Weight: 220-254
Administration / exposure
- No. of animals per sex per dose:
- 5 males
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- No mortality
- Clinical signs:
- other: No clinical signs
- Gross pathology:
- No macroscopic findings.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- According to European Union legislation substance of low toxicity (LD50 >2000 mg/kg b.w.) is not classified to the class of toxicity based on the strength of toxicity in acute exposure conditions.
- Executive summary:
The test results showed no toxicity on rats with a LD50 > 5000 mg/kg bw.
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