Registration Dossier
Registration Dossier
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EC number: 613-827-2 | CAS number: 6563-82-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 3-Hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentanone
- EC Number:
- 613-827-2
- Cas Number:
- 6563-82-2
- Molecular formula:
- C19H24O3
- IUPAC Name:
- 3-Hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentanone
Constituent 1
Results and discussion
Test results
- Species / strain:
- S. typhimurium TA 1535, TA 1537, TA 98 and TA 100
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
According to (Q)SAR modell: QSAR Toolbox, the predicted values indicated that methyl-secoolon is not mutagen.
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