Registration Dossier
Registration Dossier
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EC number: 221-077-9 | CAS number: 2999-46-4
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The bioconcentration factor (BCF) of ethyl isocyanoacetate was calculated by the EPI (Estimation Programs Interface) Suite™, a Windows®-based suite of physical/chemical property and environmental fate estimation programs developed by the EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC).
Following results for the bioconcentration factor BCF (L/kg wet weight; upper, mid and lower trophic level) were obtained:
Bioaccumulation Estimates (BCFBAF v3.01):
Log BCF from regression-based method = 0.500 (BCF = 3.162 L/kg wet-wt)
Log Biotransformation Half-life (HL) = -1.8371 days (HL = 0.01455 days)
Log BCF Arnot-Gobas method (upper trophic) = 0.078 (BCF = 1.196)
Log BAF Arnot-Gobas method (upper trophic) = 0.078 (BAF = 1.196)
log Kow used: 0.91 (estimated)
Key value for chemical safety assessment
- BCF (aquatic species):
- 3.162 L/kg ww
Additional information
Data is available from a reliable QSAR model.
Bioaccumulation of ethyl isocyanoacetate is not expected since the criterion for considering substances as being not bioaccumulative (i.e. unlikely to have a BCF > 2,000) are met as can be derived from BCF calculation. No further testing is required.
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