Registration Dossier
Registration Dossier
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EC number: 204-679-6 | CAS number: 124-09-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.2 mg/L
Additional information
One value for chronic toxicity to invertebrates was available and this was obtained from the MITI database. Notwithstanding the fact the study could not be assigned due to lack of information, the NOEC was taken as ¿ 4.2 mg/L and this reliability is supported by the relatively high values from the acute studies, (geometric mean of daphnid EC50s approximately 8 times higher). The concentrations used in the study were not extremely low and HMD is highly soluble in water so nominal concentrations could be accurately made up in the laboratory. Moreover, in a recent study on algae, the test substance was found to be stable over a 72 hour period in the presence of algae and therefore the nominals concentrations used are expected to be an accurate estimate of actual concentrations. In a weight of evidence approach, this study can be considered as acceptable for the purpose of risk assessment.
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