Registration Dossier
Registration Dossier
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EC number: 208-908-0 | CAS number: 546-67-8
Endpoint summary
Administrative data
Description of key information
Sparingly soluble lead compounds do not exhibit irritant or corrosive properties.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
No irritation studies were found specifically for lead tetraacetate. However, lead tetracetate has been classified as corrosive (Skin Corr. 1B, H314) on the basis of the presence of acetic acid (Skin Corr. 1A, H314) as an impurity in the substance. In accordance with Column 2 of Sections 8.1 and 8.2 of REACH Annex VII, corrosivity and irritation studies do not have to be conducted for lead tetraacetate on the basis that the available information indicates that the criteria are met for classification as corrosive to the skin or irritating to eyes. Respiratory irritation will not occur as the substance produces very limited to no dust.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
No irritation studies were found specifically for lead tetraacetate. However, the substance contains up to 3% of acetic acid as supplied and acetic acid is classified as corrosive. On the basis of a concentration greater than 1%, the substance is classified as corrosive, and no irritation studies are needed for lead tetraacetate. Respiratory irritation will not occur as the substance produces very limited to no dust.
Data waiver:
In accordance with Column 2 of Sections 8.1 and 8.2 of REACH Annex VII, the irritation studies do not have to be conducted for lead tetraacetate on the basis that the substance is classified as corrosive.
The following information is taken into account for any hazard / risk assessment:
The substance is considered to be corrosive because it contains acetic acid, a corrosive substance, at concentrations greater than 1%.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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