Registration Dossier
Registration Dossier
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EC number: 272-713-7 | CAS number: 68909-79-5 An inorganic pigment that is the reaction product of high temperature calcination of principally chromium (III) oxide forming a crystalline hematite. Its composition may include any one or a combination of the modifiers Al2O3, Fe2O3, or Mn2O3.
Toxicity to reproduction
Administrative data
- Endpoint:
- screening for reproductive / developmental toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because a pre-natal developmental toxicity study is available
Cross-reference
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- developmental toxicity
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Based on the explanation given in the read-across assessment framework document (attached in IUCLID section 13.2) an analogue approach for read-across of the endpoint “developmental toxicity" from the structural analogues to the target substance is considered justified.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Species:
- rat
- Key result
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Remarks:
- no effects where observed with neither of the two source substances (managnese alumina pink corundum and chromium iron oxide)
- Abnormalities:
- no effects observed
- Key result
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Remarks:
- no effects where observed with neither of the two source substances (managnese alumina pink corundum and chromium iron oxide)
- Abnormalities:
- no effects observed
- Developmental effects observed:
- no
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
