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Diss Factsheets
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EC number: 202-626-1 | CAS number: 98-00-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The predicted 96 hour fish QSAR LC50 was 361.959 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 361.959 mg/L
Additional information
A 48 -hour toxicity study in golden orfe showed a mean LC50 value of 1028 mg/L based on two independent results. The study duration is too short (48 hours instead of 96 hours).
The USEPA EPIWEB 4.0 QSAR software was used to calculate the 96 hour fish LC50. Within the software the ECOSAR module contains a library of QSARs for predicting aquatic toxicity. ECOSAR Version 1.00 has the potential to identify over 120 chemical classes and calculates QSARs for numerous endpoints and organisms. The QSARs in ECOSAR for both neutral organics and classes are based on a linear mathematical relationship between the predicted log Kow values and the corresponding log of the measured toxicity values (mmol/L) for the training set chemicals within each chemical class of interest. Specific Furfuryl Alcohol phy-chem parameters were used when running ECOSAR and included the measured log Kow for the substance. The results from ECOSAR indicated that furfuryl alcohol’s toxicity was best represented by the benzyl alcohol chemical class. The phys-chem properties of both substances were then analysed to ensure that this was indeed the case. The phys-chem data for Furfuryl Alcohol (FA) show that the substance falls within the domains (limitations) of the ECOSAR software and therefore the calculated QSARs should be Klimisch scored as 2 (reliable with restrictions). It must also be noted that a representative chemical class was found for FA in the software database and this provides additional support for the use of the QSAR. Finally, experimental results for shorter exposure periods also indicate that ecotoxicity values would all be greater 100 mg/L and therefore support the use of the QSAR.
The predicted 96 hour fish QSAR LC50 was 361.959 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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