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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Oral LD50:>2000 mg/kg bw for rat (limit test)
Dermal LD50:>2000 mg/kg bw for rat (limit test)

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

The toxic effect and death resulted at the oral dosage of 2000 mg/L is probably caused by the caustic/corrosive effect of KOH formed rapidly when potassium permanganate contacted the biological system of the animal rather than caused by potassium permanganate itself.

Result: The test substance in dose level 2000 mg/kg bw administered orally caused death of 2 animals from five.

 

-                    LD50of the test substance Potassium permanganate for female rats is higher than 2000 mg/kg bw

-                    clinical signs of intoxication were observed in all six animal

 

Result: Nontoxic for rats after single dermal application of the test substance at the dose level 2000 mg/kg bw.

-                    Potassium permanganate applied on the skin of rats at the dose level of 2000 mg/kg bw caused no death of animals

-                    no clinical signs of intoxication were observed in animals

Justification for classification or non-classification

Conclusive but not sufficient for classification.

But potassium permanganate is listed on Annex VI of CLP as Acute tox 4 so that classification will be used in the classification section.