Registration Dossier
Registration Dossier
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EC number: 479-950-7 | CAS number: 31274-51-8
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
A significant bioaccumulation is not expected
Key value for chemical safety assessment
Additional information
Two valid toxicokinetic studies (uptake, distribution, metabolisation and excretion) in rats of the substance according to OECD 417 are available. The uptake rate via the gastrointestinal tract was 0.73 and 0.06 % of the initial test substance concentration, respectively, clearly indicating a low potential for accumulation. Additionally, the high molecular diameter of 2.14 nm and the very low water solubility (< 30 ng/L) further indicates the low accumulation potential of the substance due to its limited bioavailability.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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