Registration Dossier
Registration Dossier
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EC number: 208-169-4 | CAS number: 513-79-1
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DMEL (Derived Minimum Effect Level)
- Most sensitive endpoint:
- carcinogenicity
DNEL related information
- Overall assessment factor (AF):
- 10 000
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
The most sensitive BMD10 from a rat carcinogenicity study with the the analogous substance cobalt sulfate is 0.43 mg/m3, BMDL10 is 0.233 mg/m3. The BMD10 was divided by 10000 to extrapolate to a 1:100 000 risk. Allometric scaling was not applied for interspecies extrapolation as this is thought to be covered by the use of a concentration.
0.43 mg/m3 : 10000 = 43 ng/m3. Note: the structured field above for the DMEL does not allow numbers as low as this and it was consequently left blank.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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