Registration Dossier
Registration Dossier
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EC number: 905-588-0 | CAS number: -
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The 10 hour IC50 (respiration inhibition) of o-xylene is 220 mg/kg soil.
Key value for chemical safety assessment
- Short-term EC50 for soil microorganisms:
- 220 mg/kg soil dw
Additional information
A single study to investigate the effects of o-xylene on soil microorganisms was identified. This study reported a 10 hour EC50 of 220 mg/kg nominal. Although this study does not follow the standard guidelines for measuring respiration inhibition of soil microorganisms it is well documented and scientifically acceptable. The test design uses a closed system and analytical monitoring. The exposure period is only 10 hours compared to the standard 28 days. Therefore, although we consider this test reliable, this study will not be used to derive the PNEC in the risk assessment.
The final decision letter from ECHA on the xylene isomers requested that this endpoint is completed using novel experimental data. Testing of the xylene isomers for this endpoint is currently ongoing and the dossier will be updated to include the result of this testing once it is complete.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
