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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Repeat dose oral toxicity data is not available for EC 249-109-7, but an OECD 407 study is available for an analogous substance and suitable for read across. NOAEL was 125 mg/kg/day for systemic toxicity.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
125 mg/kg bw/day
Study duration:

Additional information

Repeated oral administration to rats for 28 consecutive days resulted in chemical-related effects at dose levels of 50 to 500 mg/kg/day. A dose level of 125 mg/kg/day was considered to be the NOAEL (no observable adverse effect level) for systemic toxicity.

Justification for classification or non-classification

In accordance with EU CLP Regulation (EC) No. 1272/2008, classification is not required for prolonged exposure.