Registration Dossier
Registration Dossier
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EC number: 203-788-6 | CAS number: 110-65-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Lethal Concentration 0% (LC0): 21.5 mg/L
Lethal Concentration 50% (LC50): 76.1 mg/L
Lethal Concentration 100% (LC100): 100 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 76.1 mg/L
Additional information
The acute toxicity of 1,4 -Butynediol (B3D) to freshwater fish has been tested according to various guideline and non-guideline methods under non-GLP conditions. Tests results with Klimisch scores of at least 2 yielded 96 hr LC50 values of 53.6 mg/L (Veith, et. al., 1989) to 76.1 mg/L (Tisler, et. al., 2003), and a 96 hr NOEC of 21.5 mg/L and LC100 of 100 mg/L (BASF AG, 1988). These data indicate that 1,4 -Butynediol is moderately toxic to freshwater fish.
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