Registration Dossier
Registration Dossier
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EC number: 201-879-5 | CAS number: 89-05-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 010
- Bibliographic source:
- Category approach for PI, PAM and their salts, 2010
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- Benzene-1,2,4,5-tetracarboxylic acid
- EC Number:
- 201-879-5
- EC Name:
- Benzene-1,2,4,5-tetracarboxylic acid
- Cas Number:
- 89-05-4
- Molecular formula:
- C10H6O8
- IUPAC Name:
- benzene-1,2,4,5-tetracarboxylic acid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- mean
- Time point:
- other: 4h
- Score:
- 1.28
- Max. score:
- 8
- Reversibility:
- fully reversible within: 8d
- Irritation parameter:
- edema score
- Basis:
- mean
- Time point:
- other: 4h
- Score:
- 0.11
- Max. score:
- 8
- Reversibility:
- fully reversible within: 8d
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: 4h
- Score:
- 1.29
- Max. score:
- 8
- Reversibility:
- fully reversible within: 8d
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Classification : not irritating
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