Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
The sensitizing potential of the test item was assessed in vivo in a non-adjuvant Buehler test (OECD 406). No skin reactions were observed after the challenge exposure during the entire observation period of 48 hours (the sensitisation rate was 0%).
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Skin Sensitisation study with the substance
The potential skin sensitising properties of the test item were assessed in the guinea pig sensitisation test carried out as the non-adjuvant Buehler test using 20 test and 10 control animals. Following three epidermal induction exposures to the test article at 100 %, the animals were subjected two weeks later to a epidermal challenge exposure with the test article at the concentration of 25 %. Responses to the challenge procedure were evaluated 24 and 48 h after the end of the exposure period. No allergic or other skin reactions were observed during the entire observation period. The sensitisation rate was 0 % at 24 and 48 h after the end of the exposure period. No other signs of clinical toxicity were observed (Toxlabs Bioscience GmbH 1998).
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The test item was not sensitising to skin. Therefore no classification and labelling is warranted according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
