Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to internationally accepted guidelines but not GLP compliant

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
ASTM E 537-98 (newer version of ASTM E 537-76)
Deviations:
no
GLP compliance:
no
Type of method:
thermal analysis
Remarks:
derivatography

Test material

Constituent 1
Chemical structure
Reference substance name:
α-(2,4-dichlorophenyl)-1H-imidazole-1-ethanol
EC Number:
246-042-5
EC Name:
α-(2,4-dichlorophenyl)-1H-imidazole-1-ethanol
Cas Number:
24155-42-8
Molecular formula:
C11H10Cl2N2O
IUPAC Name:
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol
Test material form:
solid: crystalline
Details on test material:
Test item: Imidazole-ethanol (CAS: 24155-42-8)
Batch No.: L49003N
Physical state: solid, crystalline powder
Storage: 15-30°C

Results and discussion

Melting / freezing point
Melting / freezing pt.:
136 °C
Atm. press.:
ca. 101 kPa
Decomposition:
yes
Remarks:
The weightloss is 0,8% up to 156°C and 4,5% up to 250°C. (Very slow)
Sublimation:
no

Applicant's summary and conclusion

Conclusions:
The melting point of imidazole-ethanol (CAS 24155-42-8) is 136°C