Registration Dossier
Registration Dossier
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EC number: 201-304-8 | CAS number: 80-73-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study contains no details on test substance source, purity, composition, batch number or storage conditions. Although test results are reported there are significant deficiencies in experimental details such as the method of atmosphere generation.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,3-dimethylimidazolidin-2-one
- EC Number:
- 201-304-8
- EC Name:
- 1,3-dimethylimidazolidin-2-one
- Cas Number:
- 80-73-9
- Molecular formula:
- C5H10N2O
- IUPAC Name:
- 1,3-dimethylimidazolidin-2-one
- Reference substance name:
- N,N'-dimethylethyleneurea
- IUPAC Name:
- N,N'-dimethylethyleneurea
- Reference substance name:
- 1,3-dimethyl-2-imidazolidinone
- IUPAC Name:
- 1,3-dimethyl-2-imidazolidinone
- Reference substance name:
- 1,3-Dimethylethyleneurea
- IUPAC Name:
- 1,3-Dimethylethyleneurea
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- 200-300g
placed into a sealed 120-L chamber containing sample vapour (near saturation)
Administration / exposure
- Route of administration:
- other: not specified
- Type of inhalation exposure:
- whole body
- Vehicle:
- not specified
- Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- 6 h
- Details on study design:
- 14 day observation period
Results and discussion
- Mortality:
- no deaths
- Clinical signs:
- other: no signs
- Gross pathology:
- no gross legions
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
