Registration Dossier
Registration Dossier
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EC number: 235-747-3 | CAS number: 12650-88-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Lysozyme is readily biodegradable; all enzyme classes are readily biodegradable. Degradation products are primarily peptides and amino acids, then carbon dioxide and water which cause no harm to nature.
The bioconcentration potential of enzymes representing macromolecules subject to metabolism in any living organism, can generally be neglected. In particular, due to the high molecular weight of 20 kD - 80 kD, the hydrophilic properties (high water solubility, negative partition coefficient) and their immediate accessibility to metabolic processes (biotransformation) it can be excluded that enzymes will bioconcentrate.
No specific information exists on the toxicity of lysozyme, however considering that Lysozyme is naturally occurring in many organisms, such as viruses, bacteria, plants, insects, birds, reptiles and mammals and it is expected as non-toxic for aquatic and terrestrial life.
Furthermore Lysozyme is not classified as carcinogenic, mutagenic or toxic for reproduction, nor as specific target organ toxicity after repeated exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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