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EC number: 202-090-9 | CAS number: 91-68-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The Effective concentration (EC50) value of 3-diethylaminophenol in aquatic invertebrate (Daphnia magna) in a 24 hr study on the behaviour effect was estimated to be 30.87743 mg/L. But the BCF value of 3-diethylaminophenol reported was not >= 2000 as well as the substance was found to be rapidly degradable.Thus considering CLP Criteria for aquatic classification of the substance , it is concluded that 3-diethylaminophenol could not exhibit short term toxicity to aquatic invertebrate (Daphnia magna).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 30.877 mg/L
Additional information
Based on the various studies available with Klimish rating 2 for target chemical CAS NO 91-68-9 and the read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
EC50 |
30.87743 mg/l |
mortality |
24 hrs |
Daphnia magna |
Predicted data for target chemical |
2 |
EC50 |
12.68779mg/L.
|
mortality |
48 hrs |
Daphnia magna |
Predicted data for target chemical |
3 |
LC50 |
42.2 mg/L.
|
mortality |
96 hrs |
Palaemonetes pugio |
Data from publication for CAS no 108-46-3 |
4 |
LT50 |
>56 mg/L.
|
mortality |
96 hrs |
Crangon septemspinosa |
Data from publication for CAS 108-46-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that EC50 value is expected to be in range of 12 to 42 mg/l and LT50 value was found to be >56 mg/l in a 24 to 96hrs study on the basis of mortality effect. But the BCF value of 3-diethylaminophenol reported was not >= 2000 as well as the substance was found to be rapidly degradable.Thus considering the CLP Criteria for aquatic classification of the substance it is concluded that the substance 3-diethylaminophenol is not toxic to aquatic invertebrate (Daphnia magna, Palaemonetes pugio and Crangon septemspinosa)
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