Registration Dossier
Registration Dossier
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EC number: 605-150-6 | CAS number: 15848-49-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key data: EC50(48 h) = 34.2 mg/L (mean measured); NOEC(48 h) = 14.3 mg/L (mean measured); LOEC(48 h) = 29.3 mg/L (mean measured).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 34.2 mg/L
Additional information
The short-term toxicity test to aquatic invertebrates (Noack_2012) performed according to EPA OPPTS 850.1010, EPA OPPTS 850.1000 and GLP was rated with RL=1 (reliable without restrictions) and used as a key study.
Immobilisation to Daphnia magna of the test item was observed at the lowest mean measured concentration of 14.3 mg/L and greater.
Based on the mean measured concentrations of the test item, the 48-hour EC50 for Daphnia magna was calculated by sigmoidal dose-response regression to be 34.2 mg/L (95 % confidence limits: 30.9 – 42.4 mg/L). The NOEC after 48 h was 14.3 mg/L. The LOEC after 48 h was 29.3 mg/L.
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