Registration Dossier
Registration Dossier
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EC number: 201-163-2 | CAS number: 78-97-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions (non-GLP)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
- Principles of method if other than guideline:
- Method: other: 79/831 EWG, Annex V part C
- GLP compliance:
- no
Test material
- Reference substance name:
- Lactonitrile
- EC Number:
- 201-163-2
- EC Name:
- Lactonitrile
- Cas Number:
- 78-97-7
- Molecular formula:
- C3H5NO
- IUPAC Name:
- 2-hydroxypropanenitrile
- Details on test material:
- Milchsaeurenitril (Lactonitrile)
Purity: 88%
Impurities: 12% acetic acid, 0.1% hydrogen cyanide, 0.1% acetaldehyde
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 0.625 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 10 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.77 mg/L
Any other information on results incl. tables
RS-Freetext:
Time / EC0 / EC50 (95% confidential limit) / EC100
-----------------------------------------------------------
3 h / 5 / 9.7 (8.50 - 10.98) / 20
6 h / 5 / 7.3 (6.72 - 7.97) / 20
24 h / 0.625 / 2.2 (1.84 - 2.57) / 10
48 h / 0.625 / 1.8 (1.54 - 2.03) / 10
-----------------------------------------------------------
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
